According to the Saint Louis Art Museum, Mary, Lady Guildford's surname was Wooten. It also lists her year of death as 1535. However, she died in September 1558.
However, also according to the Saint Louis Art Museum, her surname was Wotton.
And according to The Met, her surname was Wotton.
So far in my research, I have only found the spelling of Wotton, except for the one example of Wooten from the Saint Louis Art Museum. I will be reaching out to the museum to inquire about the spelling of her surname, as well as correcting her year of death. I know that there was no standardized spelling in the 16th century. For example, Boleyn (as in Anne Boleyn, the 2nd wife of King Henry VIII) had her family's surname was documented as Boleyn, Buleyn, Bolen, Bulleyne, Boleyne, Bolleyne, Boyleyn, Bowleyne, Bulloigne, and Bullen.
According to FamilySearch.org,
"Mary Wotton was born in 1499, in Boughton Malherbe, Kent, England, her
father, Sir. Robert Wotton, was 44 and her mother, Anne Belknap, was
39." After 26 December, 1523, Mary became the second wife of Sir Henry
Guildford, who died on 28 May, 1532 in Kent, England. He was buried in Blackfriars, London, England.
By July 1540, Mary had married for a second time, this time to Sir Gawain Carew. She died childless in September 1558, at the age of 59.
Mary's sister was Margaret Wotton, Marchioness
of Dorset, who was the second wife of Thomas Grey, Marquess of Dorset, and
the mother of his children, including Henry Grey, Duke of Suffolk (the father of Lady Jane Grey, the 9 Days Queen of England). Two
of her brothers held important positions in the government: Edward
Wotton (knighted and later appointed sheriff of Kent) was Treasurer of
Calais and Nicholas Wotton was a diplomat who arranged the marriage of
Henry VIII to his fourth wife, Anne of Cleves, in 1539.
According to her burial plaque at St. Mary Churchyard in Devon, England, her surname was indeed Wotton.
My interpretation of the inscription above is:
Here beth buried the Lady Mary Guildford daughter … Robert
Wotton of Kent knight… wife to … Guildford knight of the garter controller of
household to the most nobull (noble) &… of England France & Ireland
defender of the faith… the wife of Sir Gawyn Carew knight who ended… the XIIII
day of September…
An interesting thing, though, is the monument erected in 1589 for Sir Gawen Carew and his wife, Mary, at Exeter Cathedral in Devon, England. Sir Gawen made his will on 11 October 1582, where he asked to buried in Exeter Cathedral, where the monument was later erected, and appointed Francis Russell, 2nd Earl of Bedford, as the overseer. He later died on 25 March 1584, according to Exeter Cathedral. The interesting thing is that Mary died in 1558 and is buried at St. Mary Churchyard in Devon, England. After Mary's death, he later remarried by 1560, this time to Elizabeth Norwich, a lady in Queen Elizabeth's household. In 1587, Lady Carew was listed as one of the ladies of the bedchamber.
So, I find it interesting that this monument in Exeter Cathedral is devoted to Sir Gawen and his first wife, whom is not buried with him (they're not even buried in the same church). This means he was married to his first wife for about 18 years and then approximately 24 years to his second wife. However, his second wife is not mentioned at all on the monument.
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